Abstract
The proportion of dietary sucrose devoted to lipid synthesis in the larvae of Drosophila melanogaster increased when the concentration was raised from 9 mM to 145 mM. A high dietary sucrose concentration increased the microsomal 9-desaturase activity and altered the specificity for de novo fatty acid synthesis termination to shorter chain lengths (14 and 16-C). Both neutral and phospholipid fatty acid contents were modified by dietary sucrose. A low environmental temperature favored the synthesis of monounsaturated fatty acids but had little effect on the length of fatty acids formed by de novo synthesis. Dietary sucrose minimized the utilization of dietary long chain fatty acids for lipid synthesis and diminished dietary fatty acid effects on fatty acid desaturation and chain elongation.
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