Effects of dietary deoxynivalenol and zearalenone on apparent ileal digestibility of amino acids in growing pigs

Abstract

This experiment was conducted to investigate the effects of deoxynivalenol (DON) and zearalenone (ZON) on the apparent ileal digestibility (AID) of AA in growing pigs. Twelve pigs (initial mean body weight=20.6±2.1kg) cannulated at the distal ileum were assigned to 3 dietary treatments in a quadruplicated 3×2 incomplete Latin square design with 3 diets and 2 periods. Three experimental diets consisted of a corn-soybean meal-based control diet, a DON-supplemented diet at 10mg/kg and a ZON-supplemented diet at 10mg/kg. All diets contained 5g/kg chromic oxide as an indigestible index. Each experimental period was comprised of a 5-d adaptation period and a 3-d ileal digesta collection period. The concentration of DON or ZON in the mycotoxin-supplemented diet was analyzed to be 11.2mg/kg or 11.6mg/kg, respectively. Pigs fed the DON-supplemented diet had less AID of Lys (0.799 vs. 0.839, P=0.08), Thr (0.695 vs. 0.751, P=0.08), Trp (0.766 vs. 0.840, P=0.02), and Val (0.687 vs. 0.749, P=0.08) than those fed the control diet, but the AID of other AA were not affected by DON supplementation. With the exception of Trp (0.771 vs. 0.840, P=0.04), the supplementation of ZON to the control diet did not affect the AID of AA. In conclusion, dietary DON, but not ZON, may reduce the AID of some indispensable AA.