Abstract
Forty mice were randomly divided into four groups on the basis of the diet to be fed as follows: 5% (low) fat diet (T1: LF); 20% (high) fat diet (T2: HF); 20% fat containing 1% conjugated linoleic acid (CLA) (T3: HFC); and 20% fat containing 1% CLA with 0.5% biopolymers (T4: HFCB). The high-fat with CLA diet groups (HFC and HFCB) and the low-fat diet group (LF) tended to have lower body weights and total adipose tissue weights than those of the high-fat diet group (HF). Serum leptin and triglyceride were significantly lower in the high fat with CLA-fed groups (HFC and HFCB) and the low-fat diet group (LF) than those in the high-fat diet group (HF). It is noteworthy that the high-fat with CLA and biopolymers group (HFCB) showed the lowest serum triglyceride and cholesterol concentrations. In the high-fat-fed group (HF), voluntary travel distance as a measure of physical activity decreased after three weeks of feeding. However, the CLA-fed groups showed increased physical activity. The groups fed high-fat diets supplemented with CLA alone and with CLA and biopolymers had higher viscosity of small intestinal contents than that in the low- and high-fat dietary groups.
Highlights
Obesity and being overweight can occur when energy intake is higher than energy expenditure
Hill et al [4] reported that consumption of a high-fat diet increases the total energy intake and that excess dietary fat is stored with greater efficiency than excess dietary carbohydrate or protein
After three weeks of feeding, the high-fat with conjugated linoleic acid (CLA) diet groups (HFC and high-fat with CLA and biopolymers group (HFCB)) and the low-fat diet group (LF) tended to have lower body weights than that of the control group (HF). This result indicates that low- and high-fat diets with CLA can suppress body weight gain; this is despite the fact that total calorie levels were the same for both the low- (5%) and high-fat (5%) diet groups
Summary
Obesity and being overweight can occur when energy intake is higher than energy expenditure. It has long been proposed that increased energy expenditure due to physical activity may be the most important factor in body weight control. Pescatello and VanHeest [1] reported that increase in obesity is due to a relatively greater decrease in physical activity rather than due to an increase in energy intake. Westerterp-Plantenga [2] reported that fat intake was related to a relatively lower satiety and that the fat content of food appears to affect meal frequency. Hill et al [4] reported that consumption of a high-fat diet increases the total energy intake and that excess dietary fat is stored with greater efficiency than excess dietary carbohydrate or protein
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