Abstract
[Purpose]We examined the effects of diet before endurance exercise on hepcidin response in young untrained females.[Methods]Ten young untrained females [age: 20.6 ± 0.8 y, height: 157.5 ± 1.0 cm, weight: 54.4 ± 1.5 kg, and maximal oxygen uptake (VO2max): 35.9 ± 1.1 mL/kg/min] were involved in two experimental conditions with a crossover design. The two conditions were separated by approximately 1 month, and each condition was performed during the follicular phase. Subjects completed 60 min of pedaling at 65% of VO2max after consuming a meal (FED) or not consuming a meal (CON). Blood samples were collected before, immediately after, and 3 h after exercise.[Results]Serum ferritin levels before exercise did not differ between the two conditions (P > 0.05). Blood glucose and lactate levels were significantly elevated immediately after exercise only under the FED condition (P < 0.05). Serum iron levels were significantly elevated after exercise under both conditions. However, the plasma interleukin-6 and serum hepcidin levels were not significantly different 3 h after exercise under either condition (P > 0.05).[Conclusion]Consuming a meal before endurance exercise at moderate intensity did not affect exercise-induced hepcidin elevation in young untrained females.
Highlights
Exercise-induced iron deficiency is a prevalent disorder among female endurance athletes[1]
respiratory exchange. ratio (RER) during endurance exercise was higher in the FED condition than in the consuming a meal (CON) condition, and a significant difference between the conditions was observed at the 55–60 min of exercise
The present study determined the effects of consuming a meal before endurance exercise on post-exercise increase in serum hepcidin levels in untrained, young females
Summary
Exercise-induced iron deficiency is a prevalent disorder among female endurance athletes[1]. Studies on hepcidin (an iron-regulating hormone) have been growing as a potential factor associated with iron deficiency in endurance athletes[6,7]. Hepcidin is a master regulator of iron metabolism[8]. Several studies have demonstrated that exercise acutely increases serum hepcidin levels during the post-exercise period[7,12,13,14]. An exercise-induced increase in the hepcidin level is generally observed following an increase in IL-6, with a peak at approximately 3 h after exercise has been completed[12,13]. Exercise in the morning may augment the exercise-induced elevation of IL-6 with a subsequent increase in serum hepcidin levels because glycogen content is lower in the morning following overnight fasting. It is possible that exercise following overnight fasting (and skipping breakfast) promotes an exercise-induced increase in serum hepcidin levels
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.