Abstract
Diazepam (1 mg/kg) was more effective than diphenylhydantoin (100 mg/kg) in suppressing motor seizures elicited in kindled rats by amygdaloid stimulation; however, the effect of these drugs on the incidence of spontaneous motor seizures in rats kindled by amygdaloid stimulation was just the opposite. At the same doses, diphenylhydantoin effectively suppressed spontaneous motor seizures, but diazepam did not. This double dissociation suggests the need for caution in drawing inferences concerning spontaneously recurring seizures from studies of elicited seizures.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
