Abstract
The influence of deltamethrin on the immune system in mice was investigated. Female BALB/c mice received deltamethrin in two daily oral doses; 6 mg/kg for 84 days and 15 mg/kg for 14 days. The humoral immune response in animals immunized with sheep red blood cells determined by agglutinin and hemagglutinin titer as well as by the number of plaque-forming cells producing IgM antibodies was significantly decreased. Also, the cell-mediated immune response assessed by alpha-naphthyl acetate esterase activity, by formation of EAC (erythrocyte-antibody-complement) rosettes, and by the footpad reaction test was hindered. A decrease in interleukin-1 activity was also ascertained. The obtained results indicate that deltamethrin exhibits an immunosuppressive effect.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
