Effects of delayed cord clamping on periventricular-intraventricular hemorrhage in preterm infant with vaginal delivery

Abstract

Objective To investigate the effect of delayed cord clamping on periventricular-intraventricular hemorrhage (PIVH) in preterm infant with vaginal delivery. Methods A total of 192 cases of preterm infant with vaginal delivery in Wuxi Maternal and Child Health Care Hospital from January 2016 to July 2017 were selected and randomly divided into delayed cord clamping group (DCC Group, 94 cases) and immediate cord clamping group (ICC group, 98 cases) . Umbilical cords were clamped after at least 60 s or until pulses diminished with no extrusion in DCC group, while in ICC group umbilical cords were clamped within 10 s. Apgar score, neonatal asphyxia, recovery situation, average arterial pressure, hemoglobin (Hb) , hematocrit (Hct) and incidence of PIVH were compared between two groups. Results The average arterial pressure, Hb at the 3rd day after the birth, and Hct of preterm infants in DCC group were (40.33±3.21) mmHg, (176.84±26.38) g/L, and (50.44±6.15) %, which were significantly higher than the ICC group (t=3.570, 3.358, 3.098; P<0.05) . The incidence of PIVH in the DCC group was 18.09%, which was significantly lower than the ICC group (30.61%) (Z=-2.018, P<0.05) . Considering the intracranial situation in preterm infant without PIVH, there were 59 cases in DCC group and 37 cases in ICC group; statistically significant difference was observed between two groups (χ2=7.693, P<0.05) . Conclusions Delayed cord clamping can effectively reduce the incidence of PIVH, and has no effect on neonatal asphyxia and recovery. Key words: Infant, premature; Delayed cord clamping; Periventricular-intraventricular hemorrhage