Abstract
Cryofrequence is the combination of cryotherapy with radiofrequency, which promotes a “thermal shock” to the tissue, working simultaneously to skin flaccidity and localized adiposity. The efficacy of dermatological and hypodermic cryofrequency treatment was evaluated. This study reports the case of a 45-year-old woman with complaints of flaccidity and fat located in the infra-umbilical region in the preoperative period of abdominoplasty. The evaluation was performed before and after treatment through evaluation protocols, ultrasound examinations and histological findings through optic microscopy, microfocal and immunohistochemical analysis. The treatment was performed in 4 sessions, with a weekly application, using the BHS 156 FULL®—BODY HEALTH BRASIL® apparatus, the parameters were temperature of -10°C, power in 70%, duration of 8 minutes. After the surgical procedure, parts of treated and untreated abdominal tissues were removed for evaluation. In the tests performed, significant destruction of adipocytes was detected, with consequent reduction of fat and greater expression of caspase-3 in the treated tissue, being constated the macrophage increase by CD68 expression. There was improvement in flaccidity, evidenced by the significant increase in the number of fibroblasts and inflammatory cells positive for Ki67, bringing more quantity and better quality to the collagen.
Highlights
IntroductionFlaccidity is considered an unsightly skin condition, this is related to the decrease of skin fibroblasts, compromising the activity of the collagen and elastin proteins responsible for the support and elasticity [4]
The analysis of CD68 expression, the treated side showed an increase in the number of macrophages (t ≤ 0.05), as demonstrated by the CD68 reaction, which represents an activation of apoptosis and activation of inflammatory cells, especially macrophages that phagocytose the apoptotic tissue
This study indicated a reduction of 3 cm in the circumference of the infra-umbilical region, a 1.0 mm increase in skinfold measurements and a reduction of 0.23 cm in the ultrasound images for the treated side, the weight and BMI did not change in an expressive manner, maintaining constant body weight suggests that the reduction of fat layer thickness was due to local treatment [12]
Summary
Flaccidity is considered an unsightly skin condition, this is related to the decrease of skin fibroblasts, compromising the activity of the collagen and elastin proteins responsible for the support and elasticity [4]. It may be a consequence of physiological aging, due to the gradual loss of skeletal muscle mass, replaced by adipose tissue, and atrophy of subcutaneous adipose tissue, among other changes [5]. There is a great demand for different non-invasive procedures, which seek to minimize aesthetic dysfunctions with minimum risks, among them is cryofrequence This technology combines cryotherapy with radiofrequency, working simultaneously in the treatment of flaccidity and localized fat. It features a tip that cools only the epidermis at about −10 ̊C, while radiofrequency heat reaches the deeper layers of the skin stimulating the formation of new collagen and elastin fibers and lipolysis [6] [7]
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