Effects of cord clamping timing in at-term elective cesarean section on maternal and neonatal outcomes: a randomized trial.

Abstract

This study aimed to compare the effects of early cord clamping (ECC), delayed cord clamping (DCC), and umbilical cord milking (MC) on maternal and neonatal outcomes in elective cesarean births. We analyzed 204 women with uncomplicated at-term singleton pregnancies, who underwent cesarean birth under regional anesthesia between March and July 2021. The women were randomized into three groups: DCC (clamped 60s postpartum), ECC (clamped within 15s postpartum), or MC (clamped after milking five times) group. The neonatal and maternal outcomes of the groups were evaluated. The duration of the operation was significantly lower (P < 0.001) in the MC group at 50min (ECC, 60min; DCC, 60min), while intraoperative bleeding was significantly higher (P < 0.001) in the ECC group at 500mL (DCC, 300mL; MC, 225mL). The rates of anemia and polycythemia significantly differed (P = 0.049) between the three groups. DCC and MC did not negatively affect maternal and neonatal outcomes compared with ECC. DCC and MC are superior to ECC in terms of short-term maternal and neonatal outcomes in cases of elective cesarean birth under regional anesthesia.