Abstract

Objective To compare the effects of continuous femoral nerve block and intravenous analgesia on postoperative analgesia and joint function after total knee arthroplasty (TKA). Methods Seventy-eight patients undergoing elective TKA surgery were divided into study group and control group according to random number table method, with 39 cases in each group. Both groups were all in the implementation of TKA, the study group were treated by continuous femoral nerve block analgesia before general anesthesia, the control group was given intravenous controlled analgesia. The postoperative complications, postoperative analgesia pump pressing times and stay in hospital for observation between the two groups, the stress indexes [fasting blood glucose (FBG), white blood cell count (WBC), C reactive protein (CRP)], resting pain patients in different periods and changes in cortisol (RVAS)after surgery, degree of pain during exercise (PVAS) and limb knee joint activity were compared between the two groups before and after operation. Results After 6, 24 and 48 hours, compared with the control group, the RVAS and PVAS scores of the study group were all lower, and the differences were significant (P 0.05). Compared with the control group, the levels of FBG, WBC, CRP and cortisol in the study group were significantly lower than those in the control group, the differences were significant (P<0.05). Compared with the control group, the study group had less pressure on the pump after the operation, the observation time was shorter, and the differences were ssignificant (P<0.05). Conclusions The analgesic of continuous femoral nerve block on TKA for postoperative analgesia, effect is significant, the stress reaction is less, which can effectively improve the TKA patients to reduce postoperative analgesia pressing times, improve limb joint activity, shorten the hospital time, and has high safety. Key words: Continuous femoral nerve block; Intravenous analgesia; Total knee arthroplasty; Analgesic effect; Joint function

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