Abstract

The Australian National Drug and Alcohol Research Centre (NDARC) devised gender-based drinking recommendations to ensure blood or equivalized breath alcohol concentrations (BrAC) remain <0.050%. However, these may be inappropriate for individuals consuming alcohol without carbohydrate (CHO), which results in higher BrACs. This study investigated the effects of ingesting alcohol with and without CHO on BrACs and simulated driving performance. Thirty-two participants (16 males; age: 23 ± 6 years) completed two randomized single-blinded trials. Participants performed a baseline drive (Drive 1), then an experimental drive (Drive 2), following alcohol consumption (males: 20 g; females: 10 g). Alcoholic beverages contained either 25 g sucrose or aspartame (AS). Driving performance was assessed using lateral control (standard deviation of lane position [SDLP] and number of lane departures) and risk-taking (number of overtaking maneuvers and maximum overtaking speed). BrAC and subjective ratings (e.g., intoxication) were also assessed. BrAC was significantly lower as Drive 2 commenced with CHO compared to AS (0.022 ± 0.008% vs. 0.030 ± 0.011%). Two males provided BrACs >0.050% with AS. Neither beverage influenced changes to simulated driving performance. Ingesting alcohol in quantities advised by the NDARC results in no detectable simulated driving impairment. However, the likelihood of exceeding the legal drink-driving BrAC is increased when alcohol is consumed with artificially-sweetened mixers.

Highlights

  • Alcohol is implicated in ~34% of fatal motor vehicle crashes each year in Australia [1], with similar rates observed among other developed nations (e.g., New Zealand (29%) [2], the US (31%) [3] and the UK (14%) [4])

  • This study examined the effects of co-ingesting alcohol with CHO or AS on simulated driving performance

  • In both males and females when alcohol is co-ingested with CHO compared to AS [15,16]

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Summary

Introduction

Alcohol is implicated in ~34% of fatal motor vehicle crashes each year in Australia [1], with similar rates observed among other developed nations (e.g., New Zealand (29%) [2], the US (31%) [3] and the UK (14%) [4]). Alcohol-involved road traffic crashes represent a significant source of unintentional injury and mortality [5]. Impairment of driving-related skills (e.g., delayed reaction time and reduced vigilance) commences at the lowest measurable blood and equivalized breath alcohol concentrations (BrACs) (i.e., >0.000% BrAC) and increases in a dose-dependent manner thereafter [6]. To reduce the incidence of road traffic crashes, many countries enact legislation that prohibits or restricts driving under the influence of alcohol [8]. In Australia, state and territory governments enforce a maximum legal driving limit of 0.050% BrAC for open class (fully-licensed), non-professional drivers [9]. Alcohol consumers are required to estimate BrAC based on drinks being consumed. Consumers have typically demonstrated a limited capacity to accurately estimate

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