Effects of combined exercise on HOMA-IR, HOMA β-cell and atherogenic index in Korean obese female

Abstract

This study attempted to provide meaningful information on the prevention of obesity and obesity-related complications. Specifically, the study attempted to verify the effectiveness of a 12-week combined aerobic and resistance training exercise program by identifying its impact on the HOMA-IR, HOMA, β-cell and the atherogenic-index (AI) among sedentary obese university students. The subjects were randomly assigned to the exercise and control groups. During a 12-week intervention, the subjects in the combined exercise group were trained 3 days per week for 80 min per day. All variables were measured 2 day before the pre- and post- of the study. Blood variables measurements included for insulin, TC, HDL-C, TG, LDL-C and glucose. Also, HOMA-IR, HOMA β-cell, A1, A2 and A3 were assessed. Two-way repeated ANOVA was performed. Interaction effects (time × group) on body fat (p = 0.017), insulin (p = 0.001), HOMA-IR (p = 0.003), HOMA β-cell (p < 0.001) and TG (p = 0.036) were observed. We conclude that 12-week of supervised combined exercise positively-affected the body fat, insulin HOMA-IR and HOMA β-cell. However, there was no significant effect on the blood lipids, TG and atherosclerosis index in our sample of Korean obese female college students.