Effects of cognitive factors on quality of life in patients with functional dyspepsia

Abstract

One hundred and eighty two outpatients with functional dyspepsia(FD)were enrolled. The cognitive questionnaire and the short form Nepean Dyspepsia Index (NDI) were used for survey. Spearman analysis showed that the cognitions of symptoms affected by emotion (r=0.284, P=0.006), somatisation symptoms induced by other diseases (r=0.211, P=0.045), and fears of cancer (r=0.217, P=0.039) were positively correlated with NDI scores. Multiple linear regression analysis demonstrated that cognition of symptoms affected by emotion (β=3.709, P=0.009), somatisation symptoms induced by other diseases (β=3.259, P=0.020), need of hospitalization (β=4.533, P=0.006), and need of medication for several years (β=-3.207, P=0.029) were associated with NDI scores. These results suggest that the quality of life might be effected by cognitive factors, and the correction of cognitive mistakes may improve quality of life of FD patients. Key words: Dyspepsia; Cognition; Questionnaires