Abstract
Numerous experiments have shown that therapeutic doses of cod-liver oil cause toxic effects and organic changes of a regressive type. Agduhr (1) demonstrated that cats and dogs showed no sign of heat when doses of 1 cc. to 5 cc. of cod-liver oil per kg./day were added to the basal diet beginning at the age of one month and continuing for one year. The number of red blood corpuscles was decreased simultaneously with a fairlysteady increase of the relative haemoglobin value. The spleen was alnuidantly supplied with blood pigments, a sign that the disintegration of red blood corpuscles was above the normal. Histological changes in different organs chiefly of a regressive nature were found but no mention was made of the thyroid gland. The weight curves of the mice as well as the microscopical examination of their organs showed many disturbing alterations. In 1925 Slagsvvold (2) noted poisoning among cattle by cod-liver oil while rodents thrived on the same oil. Norris and Church (3) point out that the toxic e...
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