Abstract
Sea nettle toxin was found to increase the short-circuit current across isolated frog skin. This effect was blocked by hyperimmune serum but not by calcium chloride. In vitro guinea pig kidney (Na + K) ATPase was unaffected by the toxin. The rise in short-circuit current was mimicked by vasopressin but tissue level of 3'5' cyclic AMP were not found to be elevated over controls.
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