Abstract
AbstractThe experiments described examine the influence of early chronic treatment with amphetamine (AMPH) or chlorpromazine (CPZ) on the formation of adult dominance behavior in two genera of mice, i.e., Peromyscus maniculatus bairdi and a random bred, Swiss albino strain of Mus musculus. It was found that AMPH‐pretreated Swiss albinos were significantly more dominant than either CPZ‐pretreated or control animals. Early drug treatment had little effect on dominance behavior of adult bairdi. These results indicate that chronic administration of certain drugs to young animals is capable of producing a quantitative change in the formation of adult behavioral patterns. Moreover, the degree to which early drug treatment alters adult behavior is influenced by the genetic background of the organism.
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