Abstract
AND CALCIUM AND BONEP;t;;BOLISM. M. Pedrazzoni, P.P. Vescovi, G. ., M. Michelini, G. Musetti, L.Maninetti, G. Zaniboni, D. Costi, M. Passeri. Istituto di Clinica Medica Generale, Universita' di Parma, Italy. Few studies have so far been performed on the effects of the chronic abuse of heroin on calcium and bone metabolism. We have examined. bv dual-photon absorptiometry, the total bodf and vertebral mineral density in 22 male heroin addicts at the start of a rehabilitation programme. Compared with normal, age-matched subjects, there was a significant decrease of vertebral bone mineral density, whereas total body mineral density and the fat and muscle mass of drug users were not significantly different from normal controls. Biochemical tests, rmed d in a subset of subjects, !n=13),
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