Abstract
The effect of chloramphenicol on ketamine anaesthesia was investigated in rabbits. In a 3-phased study, the rabbits were administered intramuscularly with 50 mg/kg body weight (bw) of ketamine alone, same dose of ketamine 30 minutes after intramuscular administration of a single dose of chloramphenicol (30 mg/kg bw) or same dose of ketamine 30 minutes after intramuscular administration of multiple dose (7 consecutive daily doses) of chloramphenicol (30 mg/kg bw). There was a significant decrease in the rabbits body temperature when ketamine was administered alone (p Key words: Chloramphenicol, ketamine, anaesthesia, microsomal, haemodynamics, induction
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