Abstract
The present study was conductedto evaluate the effect of chemical industry effluents on hematological parameters in mice. Two-week-old 128 mice were randomly divided into four groups of 32in each viz. control (group-I), R2B vaccine + effluent treated (group-2), effluent treated (group-3) and R2B vaccinated (group-4). The vaccine used was R2B strains of Raniket Disease given to group-2 and 4 @ 0.1 ml by intraperitoneal route. The hematological parametersviz. hemoglobin, packed cell volume, total erythrocyte count and differential leucocyte count were performed at fortnight interval upto 120 days of experimentation. Cell mediated immune response was measured by Lymphocyte Stimulation Test (LST). It was observed that hemoglobin, packed cell volume, total erythrocyte count, total leucocyte count and differential leucocyte count as well as lymphocyte Stimulation Index decreased significantly in effluent treated group. Significant decrease in these parameters led to anaemia and suppression of cell mediated immune response in chemical industry effluent treated micein comparison to controls.
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