Abstract
The effects of low-frequency caudate stimulation on classical leg flexion conditioning in cats were assessed. During acquisition, conditioned leg flexion was markedly impaired by caudate stimulation while the unconditioned leg flexion response was unaffected. On trials immediately following the discontinuation of caudate stimulation, asymptotic performance of conditioned leg flexion occurred. These differential inhibitory effects on learning and performance were interpreted as supporting the contention that the caudate nucleus influences the behavior of cats by modulating the elaboration of goal-directed motor responses.
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