Effects of cardiovascular events on 30-day mortality of elderly patients with severe community-acquired pneumonia

Abstract

Objective To evaluate the effect of cardiovascular events (CVE) on 30-day mortality of elderly patients with severe community-acquired pneumonia (CAP). Methods Totally 167 elderly severe CAP patients fulfilled this study inclusion criteria from January 2012 to June 2014 in Shanghai Jiaotong University Affiliated Sixth People's Hospital were enrolled. The patients were treated following CAP standard guide. CVE complications and 30-day mortality were recorded. Kaplan-Meier survival curve and multivariate logistic regression analysis were used to assess the effect of CVE on 30-day mortality. Results In total of 167 elderly patients, 86 (51.5%) patients developed CVE. The 30-day mortality was 28.7% (48/167). The 30-day mortality in the elderly severe CAP patients with CVE complications was higher than the patients without CVE complications [39.5% (34/86) vs. 17.3% (14/81), Log-rank test, χ2=10.065, P=0.002]. Multivariate logistic regression analysis showed that CVE complications was the independent risk factor of 30-day mortality for elderly CAP patients (OR=1.997, P<0.05). Conclusion CVE complications are common in elderly severe CAP patients, who are at a high risk of 30-day mortality. Key words: Community-acquired pneumonia; Cardiovascular events; Aged