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Abstract
Problem statement: To evaluate effects of oral insulin carried by camel’s milk on type 1 diabetes patient in comparison with both insulin injection requirements and camel’s milk alone. Approach: Total of fifty randomly selected type 1 diabetic subjects were divided into three groups; A, B and C (n = 15). All subjects received a usual care (diet, exercise and insulin injection) but group B subjects in addition received 500 mL day-1 of camel’s milk, while group C their subjects in addition received insulin mixed with 500 ml day-1 of camel’s milk. Blood samples were taken at beginning and at end of treatment to measure lipid profile and HbA1c % while blood glucose measured weekly. Results: Data shown significant improvements in FBG (205.3±2.16-47.26±1.89), PBG (339.86±3.18-161.26±2.89), HbA1c % (9.9±0.25±5.62±0.21) and significant reduction in insulin requirement (59.26±0.7-20±0.35) in group C receiving insulin mixed with camel’s milk in comparison with groups A and B. Conclusion: Camel’s milk mixed with insulin was indicated to be an effective supplementation, as adjunctive therapy in management of type 1 diabetes than camel milk or insulin injection.
Highlights
Type 1 diabetes mellitus is a common organ specific auto-immune and endocrine disorder, Oral insulin therapy has been known for many years but the important drawback is its coagulum formation in acidic environment such as the stomach, thereby neutralising its potency
Prevention and early treatment is important because diabetes interrupts normal developments in children and carries the threat of severe complication in more active period of life (Singh and Palmer, 2005) Its primary treatment is insulin injection replacement, at present neither entire physiological insulin replacement could be achieved in clinical practice nor could metabolic disturbances be normalized
Pozzilli et al (2000) in recentonset Type I diabetes (IMDIAB VII) study indicates that addition of 5 mg of oral insulin does not modify the course of the disease in the first year after diagnosis and probably does not statistically affect the humoral context of traditional ethno-medical practices
Summary
Type 1 diabetes mellitus is a common organ specific auto-immune and endocrine disorder, Oral insulin therapy has been known for many years but the important drawback is its coagulum formation in acidic environment such as the stomach, thereby neutralising its potency. Prevention and early treatment is important because diabetes interrupts normal developments in children and carries the threat of severe complication in more active period of life (Singh and Palmer, 2005) Its primary treatment is insulin injection replacement, at present neither entire physiological insulin replacement could be achieved in clinical practice nor could metabolic disturbances be normalized. Pozzilli et al (2000) in recentonset Type I diabetes (IMDIAB VII) study indicates that addition of 5 mg of oral insulin does not modify the course of the disease in the first year after diagnosis and probably does not statistically affect the humoral context of traditional ethno-medical practices
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