Abstract
Objective To investigate the effects of caffeine citrate on early lung function in preterm infants with apnea. Methods A total of 80 preterm infants with apnea admitted to Yuncheng Central Hospital of Shanxi Province from October 2015 to October 2018 were randomly selected, and the clinical data were retrospectively analyzed. According to the drugs used, 80 premature infants were divided into two groups, with 40 casein each group. The citrate caffeine group was given caffeine citrate, and the aminophylline group was given aminophylline. The related ventilation indexes, medication time and adverse reactions were compared between the two groups. Results The nasal continuous positive airway pressure (NCPAP)ventilation time (134±16)h, invasive ventilation time (35±7)h, oxygen time (140±40)h, and medication time (191±70)h in the citrate caffeine group were lower than those in the aminophylline group (P all 0.05). Conclusions Caffeine citrate treatment has significant effects on early lung function in preterm infants with apnea, and has a good long-term prognosis. Key words: Caffeine citrate; Apnea; Premature infant; Lung function
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