Abstract
Colonic diverticular bleeding (CDB) and acute colonic diverticulitis (ACD) show high recurrence rates. The establishment of optimal strategies that prevent the recurrence of CDB and ACD is a major concern among gastroenterologists. This study aimed to assess the efficacy of burdock tea for preventing CDB and ACD recurrences. Newly diagnosed patients with CDB (n = 91) or ACD (n = 70) were randomly assigned into two groups. The experimental group received 1.5 g of burdock tea three times a day, whereas the control group did not receive any treatment. The median (interquartile range) of observation for recurrence of CDB or ACD was 22.0 (14.1) months and 30.3 (18.6), respectively. The burdock tea treatment showed significant preventive effects on recurrence of ACD. A lower ACD recurrence rate (5/47 [10.6%] vs. 14/44 [31.8%]) and longer recurrence-free duration was observed in the burdock tea group (59.3 months [95% CI: 54.0–64.7] vs. 45.1 months [95% CI: 37.1–53.0] by the Kaplan-Meier analysis; p = 0.012 by log rank test) than in the control group, although there was no significant preventive effects on the CDB recurrence. This randomized clinical trial demonstrated that daily intake of burdock tea could be an effective strategy for prevention of ACD recurrence, but not for CDB recurrence.
Highlights
Colonic diverticular diseases (CDDs) are common in Western and industrialized societies[1]
We assessed the efficacy of burdock tea in preventing colonic diverticular bleeding (CDB) and acute colonic diverticulitis (ACD) recurrences using a randomized, controlled trial (RCT)
The results demonstrated that treatment with burdock tea has a possible preventive effect on the recurrence of ACD, but not on the recurrence of CDB
Summary
Colonic diverticular diseases (CDDs) are common in Western and industrialized societies[1]. The chief complications of CCDs are colonic diverticular bleeding (CDB) and acute colonic diverticulitis (ACD), and the incident rates of both complications have been increasing. Both CDB and ACD carry a high recurrence rate. There are three kinds of strategies to prevent the recurrence of CDB and ACD11 These are a high fiber diet or supplements, antibiotics, and anti-inflammatory agents. The pathogeneses of CDB and ACD are different, burdock tea possibly prevents the recurrence of CDB and ACD given that it is fiber-rich, and contains anti-microbial and anti-inflammatory properties. The aim of the present study was to assess the efficacy of burdock tea on preventing the recurrences of CDB and ACD using a random assignment method
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