Effects of brief monocular deprivation on binocular depth perception in the cat: A sensitive period for the loss of stereopsis

Abstract

The period of susceptibility for binocular depth vision was studied in kittens by subjecting them to periods of monocular deprivation beginning at different ages. In an initial study, we found that normally reared kittens can learn a depth-discrimination task much more rapidly when tested binocularly than monocularly, even when testing is begun as early at 30 d. In subsequent experiments, kittens were monocularly deprived by eyelid suture, following which their monocular and binocular depth thresholds were measured using the jumping-stand procedure. We obtained the following results: (1) When monocular deprivation is applied before the time of natural eye opening but is discontinued by no later than 30 d, there is very little effect on binocular depth thresholds. (2) When deprivation is begun at 90 d, binocular depth thresholds are unaffected. (3) When deprivation is begun between these two ages, the magnitude of the deficit varies with the period of deprivation and the age at which it begins. (4) By imposing brief (5 or 10 d) periods of deprivation, beginning at different ages, we were able to demonstrate that the peak of the sensitive period is between the ages of 35 and 45 d, with a fairly rapid decline in susceptibility outside those age limits. (5) Even with as little as 5 d of deprivation, substantial permanent deficits in binocular depth vision can be induced.