Effects of Breast-Conserving Surgery and Modified Radical Mastectomy on Early Breast Cancer

Abstract

To compare the effects of breast-conserving surgery and modified radical mastectomy on early breast cancer is the objective of the study. 30 early breast cancer patients undergoing breast-conserving surgery and 30 cases undergoing modified radical mastectomy from January 2019 to February 2020 were selected. Their clinical data were retrospectively analyzed. Their operation conditions, postoperative pain score, immune function indices, incidence rate of postoperative complications, postoperative incision healing time, length of stay, excellent/good rate of breast appearance and quality of life score were compared. The rate of positive resection margin and operation time had no statistically significant differences between the two groups (p>0.05). In breast-conserving group, the intraoperative blood loss was smaller (p<0.05) and the postoperative incision healing time and length of stay were shorter than those in radical mastectomy group (p<0.05). The pain scores at 1-3 d after operation significantly declined in breast-conserving group compared with those in radical mastectomy group (p<0.05). After operation, the levels of cluster of differentiation 3+ and cluster of differentiation 4/cluster of differentiation 8 significantly declined in both groups compared with those before operation, while they were higher in breast-conserving group than those in radical mastectomy group (p<0.05). The incidence rate of postoperative complications in breast-conserving group was lower than that in radical mastectomy group (3.33 % vs. 20.00 %) (p<0.05) and the excellent/good rate of breast appearance in breast-conserving group was higher than that in radical mastectomy group (96.67 % vs. 76.67 %) (p<0.05). After operation, breast-conserving group had a higher quality of life score than that of radical mastectomy group (p<0.05). Both breast-conserving surgery and modified radical mastectomy can remove tumor lesions in patients with early breast cancer. However, breast-conserving surgery is superior in decreasing intraoperative blood loss, facilitating postoperative rehabilitation, relieving postoperative pain, protecting immune function and reducing postoperative complications, thereby improving quality of life of patients.