Abstract
近年来的研究发现,支气管哮喘(简称哮喘)的发病不单单局限于气道和肺组织,还存在一个全身性的反应机制,而骨髓造血祖细胞等在哮喘发病中的作用日益受到重视.哮喘发病过程中,不仅骨髓内祖细胞增多,核糖体顺反子表达增高,而且外周血循环及局部肺组织中造血祖细胞也增多.白细胞介素-5,9,12和嗜酸性细胞趋化因子参与了这一过程.通过研究骨髓造血祖细胞等在哮喘中的作用,人们正试图寻找哮喘治疗的新途径.
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