Abstract
Ayahuasca is a hallucinogenic substance currently being investigated for the treatment of mood, anxiety, and trauma-related disorders. Evidence from animal and human studies suggest that the effects of ayahuasca involve modulation of neural substrates relevant for emotional processing, especially in regions rich in serotonergic receptors. Moreover, preclinical studies also show that ayahuasca has specific effects on fear-related memories. The serotonergic system has been classically associated to anxiety and fear responses, with selective serotonin reuptake inhibitors being first-class medication to treat mood, anxiety, and stress-related disorders. Here we review currently available data regarding ayahuasca (and its main components) behavioral and functional effects on anxiety and fear-related responses through its modulation of serotoninergic signaling.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
