Abstract

SummaryChicken and rat hypophyseal extracts were compared with a purified beef growth hormone preparation in the hypophysectomized, immature female rat using the tibial cartilage assay and hematological alterations. The avian adenohypophysis contains 1/8th of the growth-promoting material found in an equivalent amount of rat hypophyseal extract. Significant depression in hematocrit and WBSG levels occurs at doses of avian extracts which are unable to promote epiphyseal cartilage growth.

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