Abstract
Abstract Hippocampectomized and partially neodecorticated rats were trained on single alternation until similar baselines were obtained. The same doses of atropine sulfate were administered to each group and a comparison made of the dose-response curves. The partially neodecorticate, like normal animals, showed an increase in alternation errors with increasing doses of atropine sulfate. In contrast, the hippocampectomized animals showed little increase in errors with any dose. This flattening of the dose-response curve, in conjunction with other evidence, was consistent with the hypothesis that an alternative, noncholinergic system mediated response inhibition in hippocampectomized animals.
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