Abstract
The effects of various doses of atropine on aqueous humor dynamies in vervet monkeys were studied by methods giving data for intraocular pressure, recipient venous pressure, gross facility of outflow, bulk flow of anterior chamber fluid into the general circulation and bulk flow into uveoscleral routes. Atropine (3 μg/ml) perfused through the anterior chamber enhanced uveoscleral flow by 0·41±0·08 μl/min and produced a corresponding reduction in flow into the general circulation. In control eyes, after the induction of anesthesia, there was an increase in the gross facility of outflow of 0·33±0·09 μl. min−1. mmHg−1. In atropine-treated eyes there was no significant increase in facility. Atropine (3 μg/ml) did not significantly change the rate of aqueous humor production, the intraocular pressure or the recipient venous pressure. Pseudofacility was not appreciably influenced by atropine.
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