Abstract
Structural remodeling of pulmonary artery plays an important role in the maintaining of sustained pulmonary arterial hypertension (PAH). The anti-remodeling effects of statins have been reported in systemic hypertension. In this study, we investigated the effects of Ato and losartan (Los) on monocrotaline-induced pulmonary artery remodeling in rats. Forty SD rats were assigned into: normal control (Ctr), PAH, Los, Ato treated groups. The mean pulmonary arterial pressure was reduced by Los and Ato treatment (mmHg: PAH, 36.1 4.2; Los, 29.8 4.8; Ato, 27.6 4.1; P<0.05).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
