Abstract

PURPOSE: Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) has been detected in as many as 50% of patients with chronic congestive heart failure(CHF). The presence of CSR-CSA in a patient with CHF confers a worse prognosis. Unfortunately, there are few data on treating CSR-CSA in patients with CHF. The plasma concentration of several neurohormones has been shown to be independent markers of left ventricular ejection fraction(LVEF) and mortality in patients with heart failure. Our study was to compare the effects of assisted ventilation(Autoset CS, ResMed, Australia) on clinical outcomes and plasma BNP concentrations in elderly patients with heart failure and CSR-CSA.

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