Effects of Aromatic Acids on Stimulating Blood Circulation and Removing Blood Stasis

Abstract

Abstract Objective The aim of this study is to determine the effects of aromatic acids on stimulating blood circulation and removing blood stasis. Methods A systematic study of aromatic acids concentration in the herbs frequently used in Traditional Chinese Medicine (TCM) formula to stimulate blood circulation and remove blood stasis is performed to help to establish a bio-activity basis and a compatibility principle for TCM formula. Results Through the study, we find that aromatic acids' effect of stimulating blood circulation and removing blood stasis may be increased by combing with alkali. Besides, aromatic acid esters can better stimulate blood circulation and remove blood stasis. What's more, the solubilization of aromatic acids helps stimulating blood circulation and removing blood stasis. Conclusions Aromatic acids have been proved to be effective in preventing platelet aggregation and anti-thrombus. On the one hand, they have a biological contribution to TCM formula and on the other hand they improve blood circulation through working with other elements in the TCM formula. Aromatic acids make a lot of contributions to the whole TCM formula.