Abstract
Arabinosyl cytosine at very low concentrations (5–100 nmolar) inhibits the incorporation of [ 3H]thymidine into polyoma DNA of infected mouse fibroblasts without affecting the labeling of the [ 3H]dTTP pool. The specific activities of these pools were determined by a new simple method. Inhibition of DNA synthesis affects chain elongation and not initiation of new rounds of replication.
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