Abstract
Aniline hydrochloride increased the amplitude of the end-plate potentials of the frog sartorius muscle. Statistical analysis showed that the effects of aniline were purely presynaptic. The shape of the dose-release curve was similar to that of the 4-aminopyridine curve although the potency was weaker than that of 4-aminopyridine. The molecular configuration and the effect of aniline suggested that the site of action of aniline was the same as that of 4-aminopyridine.
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Schedule a callMore From: European Journal of Pharmacology: Molecular Pharmacology
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