Effects of anesthesia under BIS monitoring on postoperative cognitive dysfunction and delirium in elderly patients taking fracture surgery

Abstract

Objective To explore the effects of anesthesia under BIS monitoring on postoperative cognitive dysfunction and delirium in elderly patients taking fracture surgery. Methods The clinical data of 80 elderly patients taking fracture treated at our hospital from July, 2014 to January, 2017 were retrospectively analyzed. And the patients were divided into a control group (n=40) and an observation group (n=40) according to anesthesia monitoring methods. The control group were adjusted the anesthesia depth according to the anesthesiologist s’ experience of and the patients’ manifestation and the observation group according to the BIS monitoring value. The usages of propofol and sufentanil during operation, postoperative cognitive dysfunction, and delirium were compared between the two groups. Results The usages of propofol and sufentanil were significantly lower in the observation group than in the control group [(495.74±52.11)mg vs. (601.29±78.96)mg and (0.92±0.18)mg vs. (1.41±0.27)mg, P 0.05). The MMSE score was significantly higher in the observation group than in the control group 5 d after operation [(23.49±2.50) vs. (21.75±2.16), P<0.05]. The incidence of postoperative delirium was significantly lower in the observation group than in the control group (10.0% vs. 27.5%) (P<0.05). Conclusion Anesthesia under BIS monitoring for elderly patients taking fracture surgery can reduce the postoperative cognitive dysfunction and the incidence of delirium. Key words: BIS monitoring; Anesthesia; Senile fractures; Cognitive dysfunction; Delirium