Abstract
The effects of alcohol, 1.5 ml/kg, administered orally in a 20% solution, on the concentration of human growth hormone (HGH), free fatty acids (FFA), 11-hydroxycorticoids, glucose, and immunoreactive insulin (IRI) were studied in 11 healthy males. The results were compared with a control study in each subject in which water alone was ingested. The alcohol-consuming phase showed a significant rise in serum HGH levels, plasma 11-hydroxycorticoid concentration and a sharp drop in serum FFA levels with no change in blood glucose or serum IRI. This lowering of FFA was felt to be due to decreased influx of these acids from the fat depots. The appearance of a drop in serum FFA, along with a rise in HGH levels, suggests the possibility that these findings may be causally related.
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