Abstract
Objectives To explore the effects of aging on midgastric transverse band(MTB)and gastric emptying. Methods In our prospective study, 57 healthy volunteer were divided into young, middle and old-age groups.After taking test meal labeled by 99mTc-diethylenetriaminepentaacetic acid(99mTc-DTPA), the pictures were collected using double probe single photon emission computed tomography(SPECT). Stomach in each frame of the pictures was divided into proximal, midgastric transverse band(MTB)and distal parts.And half gastric emptying time, gastric remnant rate at 90 min, areas of different gastric parts were tested and calculated respectively. Results Half gastric emptying time of whole stomach was(43.24±11.87)min, (42.07±+ 9.31)min and(45.81±10.73)min in young, middle and old-age groups, respectively, with P>0.05.Among young, middle and old-age groups, half gastric emptying time was(38.09±10.26)min, (37.33±9.28)min and(26.74±12.07)min in proximal stomach, and it was(38.35±12.96)min, (37.73±7.46)min and(46.41±10.74)min in distal stomach, respectively.The half gastric emptying time was significantly reduced in proximal stomach and increased in distal stomach in old-age group(both P 0.05.This rate in proximal stomach was(25.01±12.35)%, (26.36±15.29)% and(19.54±8.47)% among three group, respectively.The rate in proximal stomach was(42.25±12.36)%, (41.56±9.33)% and(56.05±11.72)% among three group, respectively.The gastric remnant rate at 90min was reduced in proximal stomach and was increased in distal stomach significantly in old-age group(both P<0.05). Compared with young and middle-age group, the old-age group showed no difference in areas of total stomach in all the time, while the areas were reduced in proximal stomach and increased in distal stomach significantly from 30 min to 90 min(all P<0.05). Total stomach versus proximal and distal stomach showed no difference in count/pixel ratio in all time, while a count/pixel ratio was reduced in proximal stomach and increased in distal stomach significantly from 30 min to 90 min(both P<0.05). Both areas and count/pixel ratio of MTB at 60 min and 90 min were significantly increased in old-age group(both P<0.05). Conclusions The total gastric emptying is not delayed along with aging, while the gastric emptying is increased in proximal stomach and reduced in distal stomach in the elderly.This abnormity of intragastric distribution of food might be related with larger area of midgastric transverse band. Key words: Age factor; Gastric emptying
Published Version
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