Abstract
ObjectiveThe objective of this experiment was to characterize the mRNA expression profile of type IIb sodium-inorganic phosphate cotransporter (NaPi-IIb) and the biochemical values of serum alkaline phosphatase (AKP), calcium, inorganic phosphorus, tibial ash and minerals of broiler chickens with aging.MethodsA total of 56 one-day-old Arbor Acres male broiler chickens were used. Broiler chickens were weighed and samples were collected weekly from day 1.ResultsThe result showed that before the growth inflection point, ash, calcium, and phosphorus content in the tibia of broiler chickens increased with growth (before 3 weeks of age), although there were no significant differences in chicks at different ages in the later period of the experiment and weight gain rate was relatively slow at this stage (4 to 6 weeks). NaPi-IIb gene expression in the small intestine in the early growth stage was higher than that in the later growth stage. Expression of calbindin and the vitamin D receptor protein in the intestinal mucosa increased with age in the duodenum and jejunum. Serum AKP activity first increased and subsequently decreased after peaking at 1 week of age, but there was no significant difference after 3 weeks of age.ConclusionThese results show that compared with the early growth stage, the weight-gain rate of broiler chickens in the late growth stage gradually decreased with gradual tibia maturation, along with weaker positive transport of phosphorus in the intestine and reinforced re-absorption of phosphorus in the kidney, which might be the reason that phosphorus requirement in the late growth stage was decreased.
Highlights
Selective pressure increases the growth rate of broiler chickens, but leg weakness inadvertently evolves, which could bring economic loss and animal welfare concern
Among the bone development indexes, bone density was found to be related to calcium and phosphorus transport in the small intestine, as high bone density is regulated by increased calcium transport and decreased phosphorus transport in the small intestine [1]
The aims of this study were to demonstrate the decreased expression of NaPi-IIb transport mRNA with aging, and the changes in values of the biochemical parameters of serum alkaline phosphatase (AKP), calcium, inorganic phosphorus, tibial ash and minerals
Summary
The objective of this experiment was to characterize the mRNA expression profile of type IIb sodium-inorganic phosphate cotransporter (NaPi-IIb) and the biochemical values of serum alkaline phosphatase (AKP), calcium, inorganic phosphorus, tibial ash and minerals of broiler chickens with aging. Results: The result showed that before the growth inflection point, ash, calcium, and phos phorus content in the tibia of broiler chickens increased with growth (before 3 weeks of age), there were no significant differences in chicks at different ages in the later period of the experiment and weight gain rate was relatively slow at this stage (4 to 6 weeks).
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