Effects of aflatoxin-detoxifizyme on growth performance and liver biochemical indices of broilers fed with aflatoxin B1

Abstract

Aflatoxin-detoxifizyme (ADTZ) was evaluated for its ability to reduce the deleterious effects of aflatoxin B1 (AFB1) in broiler diets. A total of 624 one-day-old AA broilers were randomly divided into 3 treatment groups with 8 replicates each. The control, AFB1 and ADTZ treatments were fed with basal diet, basal diet + 0.1 mg/kg AFB1 and basal diet + 0.1 mg/kg AFB1 + 0.3% ADTZ, respectively. The trials lasted 42 days. The results showed that: (1) AFB1 diminished the growth performance of broilers significantly (P < 0.01). (2) The AFB1 supplement caused significant alteration of related liver enzyme activities and significantly decreased the body’s antioxidant capacity. (3) Related parameters were returned to normal levels by a 0.3% ADTZ addition to the AFB1-contaminated diet. All the results in the trials indicate that ADTZ has the ability to detoxify AFB1 and recover the negative effects of AFB1.