Effects of Adjuvant Dexketoprofen in Regional Intravenous Anesthesia

Abstract

Background and objectives: In our study, it is aimed to investigate the effectiveness of the use of local anesthetics by the addition of adjuvant drugs to the patients who had hand surgery with regional intravenous anesthesia. In this context, contributions of non-steroidal anti-inflammatory agent to the local anesthetics as adjuvant medication during and after surgery for the patients and their positive and negative effects on the patients were evaluated. Methods: The Study was designed to cover backward date range of January 2010-August 2011 period of University Hospital Operating Room records of the hand surgery patients operated with regional intravenous anesthesia (RIVA) and those were evaluated. Total 44 patients’ records retrospectively evaluated. The patients treated with prilocaine were selected as control group (Group 1), the other 22 patients treated with prilocaine and Dexketoprofen were selected as the adjuvant drug added group for the RIVA process (Group 2). The sensory and motor block onset and end times of the patients, the surgical wound pain VAS values and also VAS scores that could be derived from tourniquet pain were examined. Results: We found the positive impact on the patients, in terms of pain, as statistically significant, by the use of non-steroidal anti-inflammatory drug as an adjuvant, during and after surgery, for the RIVA technique. In this study, the starting and ending times of sensory and motor block, surgical wound VAS scores, tourniquet VAS scores measurements were taken. The mean onset time of sensorial block of Group I was calculated as 9.4 min, whereas Group II, mean onset time of sensorial block was calculated 7.09 min. In Group 2, 40 Minutes after the tourniquet had a lower VAS scores. Conclusion: It is concluded that, in the first 24 hours in RIVA, intraoperative and postoperative analgesic requirement was reduced by Dexketoprofen.