Abstract
Heat and moisture exchangers (HME) can be used as artificial noses in intubated patients undergoing invasive mechanical ventilation. Intravenous furosemide (F) is widely used in the ICU for volume control. Furosemide could act on respiratory mucus either directly by inhibiting NaK(Cl)2 cotransporter or indirectly by promoting intravascular volume depletion. The aim of this study was to determine the effects of acute systemic dehydration promoted by IV furosemide on respiratory mucus properties, transportability and tracheal transepithelial potential difference in dogs.
Highlights
Heat and moisture exchangers (HME) can be used as artificial noses in intubated patients undergoing invasive mechanical ventilation
Effects of acute systemic dehydration promoted by intravenous furosemide on respiratory mucus in dogs
Furosemide could act on respiratory mucus either directly by inhibiting NaK(Cl)[2] cotransporter or indirectly by promoting intravascular volume depletion
Summary
Heat and moisture exchangers (HME) can be used as artificial noses in intubated patients undergoing invasive mechanical ventilation. Effects of acute systemic dehydration promoted by intravenous furosemide on respiratory mucus in dogs NK Nakagawa,Aff[1] F Donato,Aff[1] CS Kondo,Aff[1] ET Guimarães,Aff[1] M King,Aff[1] PHN Saldiva,Aff[1] G Lorenzi-Filho,Aff[1]
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