Effects of Acupuncture & Qigong Meditation on Nonmotor Symptoms of Parkinson’s Disease

Abstract

Background: Parkinson's disease(PD) affects not only motor symptoms, but also nonmotor symptoms. This study is a clinical trial to determine whether Qigong and acupuncture affect nonmotor symptoms of PD.Methods: A 2-arm parallel and randomized trial was performed with 21 participants who had received either Qigong meditation only [control group (CG)] or acupuncture and Qigong meditation [experimental group (EG)]. The participants' levels of the discomfort in nonmotor symptoms from Parkinson's disease were evaluated by using the Unified Parkinson's Disease Rating Scales (UPDRS 1) and Test of Smell Identification (TSI) before and after 12 treatments at baseline and 1 month after 12 treatments.Results: The both CG and EG showed improvements in the UPDRS 1 score after treatment by 5.6 ± 5.15 (<i>p</i>= 0.003; 74%) and 4.8 ± 3.80 (<i>p</i> = 0.004; 79%), respectively. The both CG and the EG did improvements in the TSI after treatment by 10.3 ± 4.37 (<i>p</i> < 0.001; 84%) and 12.6 ± 1.77 (<i>p</i> = 0.022; 100%), respectively. However, statistical differences were not observed between the CG and the EG using the UPDRS 1 and the TSI scores.Conclusion: The combination of Qigong and acupuncture and Qigong alone was shown to improve the nonmotor symptoms and olfactory function of PD. In the future, large-scale clinical studies on alternative treatment for PD and studies on mechanisms affecting nonmotor symptoms of acupuncture and Qigong are needed.