Abstract
This study was to examine the effects of acupressure on fatigue and depression in HCC patients undergoing TACE. A quasiexperimental study design was used. Patients were evaluated at five time points: before treatment (T1) and 2, 3, 4, and 5 days after treating TACE (T2, T3, T4, and T5). Fatigue and depression were assessed by a VAS fatigue scale and a VAS depression scale at each time point. TFRS and BDI were administered at T1 and T5. Patients' fatigue and depression were significantly higher at T5 than at T1 in two groups. Fatigue and depression increased in both the experimental and control groups' patients over the five days of hospitalization during which TACE and chemotherapy were administered. The experimental group had significantly less fatigue than the control group, with lower subscale scores on physical, psychosocial, daily, and overall fatigue. There were no differences between the groups on depression. At posttest, the experimental group experienced lower physical, psychosocial, daily, and overall fatigue than the control group. Acupressure can improve fatigue in HCC patients during treatment with TACE but did not alleviate depression. Discharge planning should include home care for management of fatigue and depression.
Highlights
Hepatocellular carcinoma (HCC) is the major cause of health problems in many developed countries and varies according to geographic location [1]
Research verified that Taiwanese patients with HCC receiving Transcatheter arterial chemoembolization (TACE) experienced moderate levels of fatigue which peaked at 2 days after initial TACE [9]
The aim of this study was to explore the effects of acupressure on fatigue and depression in HCC patients treated with transcatheter arterial chemoembolization
Summary
Hepatocellular carcinoma (HCC) is the major cause of health problems in many developed countries and varies according to geographic location [1]. Fatigue and depression are reported as the most common problems for HCC patients treated with TACE [4,5,6,7]. Unrelieved fatigue and depression may cause patients to withdraw from treatment and can negatively impact quality of life. Some reports have shown that HCC patients have significant fatigue and depression gradually increasing during treatment. In several studies [4,5,6, 10] of HCC patients receiving TACE, it was reported that fatigue was the most common adverse effect causing sleep disturbances [5], reduced physical and emotional status [11], and produced a negative effect on overall quality of life [12]
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