Abstract

Effects of active immunization against the recombinant second extracellular loop of sheep β<sub>2</sub>-adrenoceptor on growth and blood biochemical parameters of female rats

Highlights

  • Leaner carcass production in the husbandry has been emphasized because of the declining demand for animal fat and the increasing demand for lean meat. β-adrenoceptors (β-ARs) are involved in adipose tissue lipolysis and protein deposition in human and animal modulated by β-agonists (Langin, 2006)

  • We investigated effects of active immunization with the recombinant fusion protein on feed intake and growth of rats

  • Growth performance and feed intake of rats were not affected by active immunization with recombinant fusion protein (rBAR) (Table 2)

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Summary

Introduction

Leaner carcass production in the husbandry has been emphasized because of the declining demand for animal fat and the increasing demand for lean meat. β-adrenoceptors (β-ARs) are involved in adipose tissue lipolysis and protein deposition in human and animal modulated by β-agonists (Langin, 2006). Leaner carcass production in the husbandry has been emphasized because of the declining demand for animal fat and the increasing demand for lean meat. Β-adrenoceptors (β-ARs) are involved in adipose tissue lipolysis and protein deposition in human and animal modulated by β-agonists (Langin, 2006). Carcass composition and feed efficiency of domestic animals can be improved by using β-agonists, such as clenbuterol, ractopamine and zilpaterol (Scramlin et al, 2010). Detrimental effects of these compounds are obviously. They are generally heat-stable and orally active, and have the potential to affect human’s health if consumed accidentally (Mersmann, 1998). Β-agonists are forbidden to use in livestock production in many countries. It is necessary to focus research efforts on developing new and safe ways to manipulate animal growth

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