Abstract
Hematocrit ratio, hemoglobin concentration and blood oxygen affinity, Bohr effect factor and Hill coefficient, adenosine triphosphate and inositol pentaphosphate (IPP) concentrations were studied in blood of adult pigeons exposed first at 140 m, and then for 3 weeks at 4000 m in an altitude chamber. At altitude, the hematocrit ratio and hemoglobin concentration significantly increased, IPP concentration decreased, and P 50 did not change. A lower mean red cell age and a higher hemoglobin concentration may account for the unchanged P 50. Adaptation to hypoxia of the tissue oxygen supply was shown by a greater blood O 2 capacitance (ΔC HbO 2/Δ o 2 ) in the physiological range of oxygen partial pressures.
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