Abstract
BackgroundAnxiety and postpartum depression are the most common psychological problems in women after delivery. Cognitive behavior intervention has been reported to have an effect in the therapy of postpartum depression. This research aimed to investigate whether cognitive behavior intervention could prevent the pathogenesis of postpartum depression in primiparous women.MethodsIn this randomized controlled trial, primiparous women who were prone to postpartum depression were recruited. Participates in the control group received routine postpartum care and those in the intervention group received both routine postpartum care and cognitive behavior intervention. Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Edinburgh Postpartum Depression Scale (EPDS) and Pittsburgh Sleep Quality Index (PSQI) were evaluated before and after the intervention.ResultsIn the intervention group, the post-intervention scores of HAMA, HAMD, EPDS and PSQI were all significantly lower than the baseline scores (p = 0.034, p = 0.038, p = 0.004, p = 0.014, respectively). The proportion of participants with postpartum depression in the intervention group (11.5%) was significantly lower than the control group (24.3%) after the 6-week intervention. Participants in the intervention group were significantly more satisfied with the care than those in the control group (p = 0.032).ConclusionThis research provided evidence that cognitive behavioral intervention in postpartum period could alleviate anxiety and depression in primiparous women, and inhibit the pathogenesis of postpartum depression.Trial registry This clinical trial was registered in the Chinese Clinical Trial Registry (ChiCTR2000040076).
Highlights
Anxiety and postpartum depression are the most common psychological problems in women after delivery
Trial registry This clinical trial was registered in the Chinese Clinical Trial Registry (ChiCTR2000040076)
Research framework of this study is shown in Fig. 1. 843 primiparous women were assessed for eligibility. 102 patients refused to participate in this research and 481 patients did not meet the inclusion criteria. 260 participants were randomly assigned into the intervention group (n = 130) and the control group (n = 130)
Summary
Anxiety and postpartum depression are the most common psychological problems in women after delivery. This research aimed to investigate whether cognitive behavior intervention could prevent the pathogenesis of postpartum depression in primiparous women. Pregnancy and delivery are two important physiological phenomena for women In this process, the pregnant woman’s mood will change and become sensitive to psychological stimuli, leading to potential psychological problems [1], such as anxiety, depression and Impaired sleep duration and quality have been associated with concurrent mood disturbance and with increased risk of future mood problems during pregnancy and the postpartum period [6]. As the most crucial postpartum stress complication, postpartum depression triggers increased vulnerability in both mothers and infants [10]. Postpartum depression is a major threat to the relationship between mother and infant [11]. Longer period of depression triggers complications that further enhances its severity [12]
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