Abstract
Purpose. Meibomian gland dysfunction (MGD) can lead to abnormalities in the composition and function of tear film, resulting in dry eye. Eyelid hygiene is a key to management of MGD. We tested a novel eyelid shampoo (Eye Shampoo Long, ESL) for its ability to maintain lid hygiene. This shampoo is nonirritating and can potentially lengthen eyelashes. This study was aimed to evaluate the efficacy of ESL in the treatment of MGD and its effects on eyelash length. Methods. Ten patients with MGD and 10 healthy subjects without MGD applied ESL twice daily for 8 weeks. Patients were examined for lid margin and dry eye before and after the trial. Subjective symptoms were evaluated. Eyelash length was measured at baseline and at the end of the trial. Results. In the MGD group, significant improvements were observed in subjective symptoms obstruction of the meibomian orifice, secretion of meibum, eyelashes contamination, eyelid margin foam, and SPK. Eyelash length became significantly longer. Conclusions. Maintaining eyelid hygiene using ESL improved the eyelid margins and symptoms of dry eye in MGD patients and increased eyelash length. These findings are promising and warrant confirmation in a larger randomized controlled study.
Highlights
Meibomian gland dysfunction (MGD) is a chronic, diffuse abnormality of the meibomian glands
MGD can be divided into low-delivery and high-delivery states based on meibomian gland secretions
The resulting increase in tear film osmolality leads to ocular surface damage [3]
Summary
Meibomian gland dysfunction (MGD) is a chronic, diffuse abnormality of the meibomian glands It is commonly characterized by obstruction of the terminal ducts and qualitative and/or quantitative changes in glandular secretions [1]. These can cause changes in tear film, eye irritation, clinically apparent inflammation, and diseases of the ocular surface [2]. Obstructive MGD is the most common form of dry eye and is categorized as a low-delivery state [2]. It is a major cause of evaporative dry eye disease. The resulting increase in tear film osmolality leads to ocular surface damage [3]
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