Abstract
Despite technical advances, the incidence of anastomotic leaks in elective colorectal surgery remains around 14%. Recent studies suggest that the use of low-energy lasers may enhance wound healing in different tissues in a selective, nondestructive manner. Based on these findings we have attempted to provide experimental background on the effects of a He-Ne laser during the early stages of healing in 155 colonic anastomoses performed on rats. The irradiation (external or endoscopical) ofthe anastomoses by repeated doses below 4 J/cm<sup>2</sup> suggest (1) the laser-induced enhancement of anastomotic healing can be obtained in both healthy colons or in situations in which anastomotic breakdown is more likely, such as colonic obstruction; (2) the photochemical effects observed can be transmitted through optic fibers; (3) energy densities above the range of 4 J/cm<sup>2</sup> show no benefit in wound-healing stimulation.
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